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ODM-guided fluid management has been shown to reduce complications and length of hospital stay after surgery in multiple randomised controlled trials (RCTs) across different types of surgery. Every randomised controlled ODM trial has been positive.
These trials have been subject to a number of meta-analyses and systematic reviews:
- Two meta-analyses re ODM in abdominal surgery published1,2
- One meta-analysis re ODM across all applications published3
- A second meta-analysis re ODM in all settings presented4
- A health technology assessment (HTA) published by ECRI for the Agency for Healthcare Research & Quality (AHRQ)5
- A report by the Centers for Medicare and Medicaid Services based upon the ECRI HTA6
- A report by the UK Centre for Evidence-based Purchasing (CEP)7
- An HTA by the Aberdeen University Health Economic Research Unit commissioned by NIHR8
- A draft HTA re ODM in colorectal surgery by the Spanish government's Entralgo Agency9 and
- Assessment of ODM evidence as Level 1A for abdominal surgery and Level 1B for orthopedic surgery for UK consensus fluid guidelines10
All the above have concluded positively on the benefits of ODM. In effect the AHRQ/ECRI report concluded that, for a large group of surgical patients, no further clinical trials on ODM were necessary.
References
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iDGFM
